US approves first gene therapy for rare form of hearing loss
via Punch Nigeria2 min read
US health officials have approved Otarmeni, a gene therapy developed by American biotechnology company Regeneron, to treat a rare form of hereditary hearing loss. This treatment targets severe-to-profound hearing loss caused by specific mutations in the OTOF gene, which affects approximately 50 newborns annually in the US. The OTOF gene encodes a protein essential for transmitting auditory signals from the inner ear to the brain. Regeneron plans to offer this treatment free of charge to eligible American patients, despite gene therapies typically being very expensive. Administered as a single injection into the ear, the therapy has been praised by parents of children who received it. A clinical trial involving 20 pediatric patients aged 10 months to 16 years showed that at least 80 percent experienced significant hearing improvement within a few months. Dr. Eliot Shearer, an ear, nose, and throat doctor at Boston Children’s Hospital involved in the trial, stated that the FDA's accelerated approval signifies a new era in treating genetic forms of hearing loss, making 24/7 natural hearing possible.
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This summary was AI-generated from a story originally published by Punch Nigeria.
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